Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases

Direct determination of RNA structures and interactions in living cells is critical for understanding their functions in normal physiology and disease states. Here, we present PARIS2, a dramatically improved method for RNA duplex determination in vivo with >4000-fold higher efficiency than previo...

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Detalles Bibliográficos
Autores principales: Zhang, Minjie, Li, Kongpan, Bai, Jianhui, Velema, Willem A., Yu, Chengqing, van Damme, Ryan, Lee, Wilson H., Corpuz, Maia L., Chen, Jian-Fu, Lu, Zhipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058046/
https://www.ncbi.nlm.nih.gov/pubmed/33879794
http://dx.doi.org/10.1038/s41467-021-22552-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058046/
https://www.ncbi.nlm.nih.gov/pubmed/33879794
http://dx.doi.org/10.1038/s41467-021-22552-y

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