Effect of TAAR1/5-HT(1A) agonist SEP-363856 on REM sleep in humans

SEP-363856 is a trace amine-associated receptor 1 (TAAR1) and 5-hydroxytryptamine type 1A (5-HT(1A)) agonist, currently in Phase 3 clinical trials for the treatment of schizophrenia. Although SEP-363856 activates TAAR1 and 5-HT(1A) receptors in vitro, an accessible marker of time- and concentration-...

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Detalles Bibliográficos
Autores principales: Hopkins, Seth C., Dedic, Nina, Koblan, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058073/
https://www.ncbi.nlm.nih.gov/pubmed/33879769
http://dx.doi.org/10.1038/s41398-021-01331-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058073/
https://www.ncbi.nlm.nih.gov/pubmed/33879769
http://dx.doi.org/10.1038/s41398-021-01331-9

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