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Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells

Pancreatic ductal adenocarcinoma (PDAC) has a collagen-rich dense extracellular matrix (ECM) that promotes malignancy of cancer cells and presents a barrier for drug delivery. Data analysis of our published mass spectrometry (MS)-based studies on enriched ECM from samples of progressive PDAC stages...

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Detalles Bibliográficos
Autores principales: Tian, Chenxi, Huang, Ying, Clauser, Karl R., Rickelt, Steffen, Lau, Allison N., Carr, Steven A., Vander Heiden, Matthew G., Hynes, Richard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058088/
https://www.ncbi.nlm.nih.gov/pubmed/33879793
http://dx.doi.org/10.1038/s41467-021-22490-9