Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis

In healthy joints, synovial fibroblasts (SFs) provide the microenvironment required to mediate homeostasis, but these cells adopt a pathological function in rheumatoid arthritis (RA). Carbohydrates (glycans) on cell surfaces are fundamental regulators of the interactions between stromal and immune c...

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Detalles Bibliográficos
Autores principales: Wang, Yilin, Khan, Aneesah, Antonopoulos, Aristotelis, Bouché, Laura, Buckley, Christopher D., Filer, Andrew, Raza, Karim, Li, Kun-Ping, Tolusso, Barbara, Gremese, Elisa, Kurowska-Stolarska, Mariola, Alivernini, Stefano, Dell, Anne, Haslam, Stuart M., Pineda, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058094/
https://www.ncbi.nlm.nih.gov/pubmed/33879788
http://dx.doi.org/10.1038/s41467-021-22365-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058094/
https://www.ncbi.nlm.nih.gov/pubmed/33879788
http://dx.doi.org/10.1038/s41467-021-22365-z

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