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Importance of sex and trauma context on circulating cytokines and amygdalar GABAergic signaling in a comorbid model of posttraumatic stress and alcohol use disorders

Alcohol use disorder (AUD) and anxiety disorders are frequently comorbid and share mechanisms that could be therapeutic targets. To facilitate mechanistic studies, we adapted an inhibitory avoidance-based “2-hit” rat model of posttraumatic stress disorder (PTSD) and identified predictors and biomark...

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Detalles Bibliográficos
Autores principales: Steinman, Michael Q., Kirson, Dean, Wolfe, Sarah A., Khom, Sophia, D’Ambrosio, Shannon R., Bagsic, Samantha R. Spierling, Bajo, Michal, Vlkolinský, Roman, Hoang, Noah K., Singhal, Anshita, Sureshchandra, Suhas, Oleata, Christopher S., Messaoudi, Ilhem, Zorrilla, Eric P., Roberto, Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058115/
https://www.ncbi.nlm.nih.gov/pubmed/33087855
http://dx.doi.org/10.1038/s41380-020-00920-2