Human ALKBH6 Is Required for Maintenance of Genomic Stability and Promoting Cell Survival During Exposure of Alkylating Agents in Pancreatic Cancer

Alpha-ketoglutarate-dependent dioxygenase (ALKBH) is a DNA repair gene involved in the repair of alkylating DNA damage. There are nine types of ALKBH (ALKBH1-8 and FTO) identified in humans. In particular, certain types of ALKBH enzymes are dioxygenases that directly reverse DNA methylation damage v...

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Detalles Bibliográficos
Autores principales: Zhao, Shengyuan, Devega, Rodan, Francois, Aaliyah, Kidane, Dawit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058185/
https://www.ncbi.nlm.nih.gov/pubmed/33897761
http://dx.doi.org/10.3389/fgene.2021.635808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058185/
https://www.ncbi.nlm.nih.gov/pubmed/33897761
http://dx.doi.org/10.3389/fgene.2021.635808

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