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Human ALKBH6 Is Required for Maintenance of Genomic Stability and Promoting Cell Survival During Exposure of Alkylating Agents in Pancreatic Cancer

Alpha-ketoglutarate-dependent dioxygenase (ALKBH) is a DNA repair gene involved in the repair of alkylating DNA damage. There are nine types of ALKBH (ALKBH1-8 and FTO) identified in humans. In particular, certain types of ALKBH enzymes are dioxygenases that directly reverse DNA methylation damage v...

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Detalles Bibliográficos
Autores principales:	Zhao, Shengyuan, Devega, Rodan, Francois, Aaliyah, Kidane, Dawit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058185/ https://www.ncbi.nlm.nih.gov/pubmed/33897761 http://dx.doi.org/10.3389/fgene.2021.635808

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