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Omega-3 Polyunsaturated Fatty Acid Intervention Against Established Autoimmunity in a Murine Model of Toxicant-Triggered Lupus

Workplace exposure to respirable crystalline silica dust (cSiO(2)) has been etiologically linked to the development of lupus and other human autoimmune diseases. Lupus triggering can be recapitulated in female NZBWF1 mice by four weekly intranasal instillations with 1 mg cSiO(2.) This elicits inflam...

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Detalles Bibliográficos
Autores principales: Pestka, James J., Akbari, Peyman, Wierenga, Kathryn A., Bates, Melissa A., Gilley, Kristen. N., Wagner, James G., Lewandowski, Ryan P., Rajasinghe, Lichchavi D., Chauhan, Preeti S., Lock, Adam L., Li, Quan-Zhen, Harkema, Jack R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058219/
https://www.ncbi.nlm.nih.gov/pubmed/33897700
http://dx.doi.org/10.3389/fimmu.2021.653464