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Drug-resistant cancer cell-derived exosomal EphA2 promotes breast cancer metastasis via the EphA2-Ephrin A1 reverse signaling

Tumor metastasis induced by drug resistance is a major challenge in successful cancer treatment. Nevertheless, the mechanisms underlying the pro-invasive and metastatic ability of drug resistance remain elusive. Exosome-mediated intercellular communications between cancer cells and stromal cells in...

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Detalles Bibliográficos
Autores principales: Gao, Zicong, Han, Xingxing, Zhu, Yuying, Zhang, He, Tian, Ran, Wang, Zhiyong, Cui, Yanfen, Wang, Zhaosong, Niu, Ruifang, Zhang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058342/
https://www.ncbi.nlm.nih.gov/pubmed/33879771
http://dx.doi.org/10.1038/s41419-021-03692-x