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Reaction lumping in metabolic networks for application with thermodynamic metabolic flux analysis

Thermodynamic metabolic flux analysis (TMFA) can narrow down the space of steady-state flux distributions, but requires knowledge of the standard Gibbs free energy for the modelled reactions. The latter are often not available due to unknown Gibbs free energy change of formation [Formula: see text]...

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Detalles Bibliográficos
Autores principales: Seep, Lea, Razaghi-Moghadam, Zahra, Nikoloski, Zoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058346/
https://www.ncbi.nlm.nih.gov/pubmed/33879809
http://dx.doi.org/10.1038/s41598-021-87643-8