Discovery of Kasugamycin as a Potent Inhibitor of Glycoside Hydrolase Family 18 Chitinases

Kasugamycin, a well-known aminoglycoside antibiotic, has been used widely in agriculture and medicine to combat microbial pathogens by binding the ribosome to inhibit translation. Here, kasugamycin was discovered to be a competitive inhibitor of glycoside hydrolase family 18 (GH18) chitinases from t...

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Detalles Bibliográficos
Autores principales: Qi, Huitang, Jiang, Xi, Ding, Yi, Liu, Tian, Yang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058351/
https://www.ncbi.nlm.nih.gov/pubmed/33898519
http://dx.doi.org/10.3389/fmolb.2021.640356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058351/
https://www.ncbi.nlm.nih.gov/pubmed/33898519
http://dx.doi.org/10.3389/fmolb.2021.640356

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