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Identification and Characterization of Zika Virus NS5 Methyltransferase Inhibitors

The recurring outbreak of Zika virus (ZIKV) worldwide makes an emergent demand for novel, safe and efficacious anti-ZIKV agents. ZIKV non-structural protein 5 (NS5) methyltransferase (MTase), which is essential for viral replication, is regarded as a potential drug target. In our study, a luminescen...

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Detalles Bibliográficos
Autores principales: Song, Weibao, Zhang, Hongjuan, Zhang, Yu, Chen, Ying, Lin, Yuan, Han, Yanxing, Jiang, Jiandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058401/
https://www.ncbi.nlm.nih.gov/pubmed/33898335
http://dx.doi.org/10.3389/fcimb.2021.665379