TET-dependent GDF7 hypomethylation impairs aqueous humor outflow and serves as a potential therapeutic target in glaucoma

Glaucoma is the leading cause of irreversible vision loss, affecting more than 70 million individuals worldwide. Circulatory disturbances of aqueous humor (AH) have long been central pathological contributors to glaucomatous lesions. Thus, targeting the AH outflow is a promising approach to treat gl...

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Detalles Bibliográficos
Autores principales: Wan, Peixing, Long, Erping, Li, Zhidong, Zhu, Yingting, Su, Wenru, Zhuo, Yehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058441/
https://www.ncbi.nlm.nih.gov/pubmed/33388417
http://dx.doi.org/10.1016/j.ymthe.2020.12.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058441/
https://www.ncbi.nlm.nih.gov/pubmed/33388417
http://dx.doi.org/10.1016/j.ymthe.2020.12.030

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