Structural and Electrophysiological Changes in a Model of Cardiotoxicity Induced by Anthracycline Combined With Trastuzumab

BACKGROUND: Combined treatment with anthracyclines (e.g., doxorubicin; Dox) and trastuzumab (Trz), a humanized anti-human epidermal growth factor receptor 2 (HER2; ErbB2) antibody, in patients with HER2-positive cancer is limited by cardiotoxicity, as manifested by contractile dysfunction and arrhyt...

Descripción completa

Detalles Bibliográficos
Autores principales: Altomare, Claudia, Lodrini, Alessandra Maria, Milano, Giuseppina, Biemmi, Vanessa, Lazzarini, Edoardo, Bolis, Sara, Pernigoni, Nicolò, Torre, Eleonora, Arici, Martina, Ferrandi, Mara, Barile, Lucio, Rocchetti, Marcella, Vassalli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058443/
https://www.ncbi.nlm.nih.gov/pubmed/33897465
http://dx.doi.org/10.3389/fphys.2021.658790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058443/
https://www.ncbi.nlm.nih.gov/pubmed/33897465
http://dx.doi.org/10.3389/fphys.2021.658790

Ejemplares similares