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Structural and Electrophysiological Changes in a Model of Cardiotoxicity Induced by Anthracycline Combined With Trastuzumab

BACKGROUND: Combined treatment with anthracyclines (e.g., doxorubicin; Dox) and trastuzumab (Trz), a humanized anti-human epidermal growth factor receptor 2 (HER2; ErbB2) antibody, in patients with HER2-positive cancer is limited by cardiotoxicity, as manifested by contractile dysfunction and arrhyt...

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Detalles Bibliográficos
Autores principales:	Altomare, Claudia, Lodrini, Alessandra Maria, Milano, Giuseppina, Biemmi, Vanessa, Lazzarini, Edoardo, Bolis, Sara, Pernigoni, Nicolò, Torre, Eleonora, Arici, Martina, Ferrandi, Mara, Barile, Lucio, Rocchetti, Marcella, Vassalli, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058443/ https://www.ncbi.nlm.nih.gov/pubmed/33897465 http://dx.doi.org/10.3389/fphys.2021.658790

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