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sEVs from tonsil-derived mesenchymal stromal cells alleviate activation of hepatic stellate cells and liver fibrosis through miR-486-5p

Mesenchymal stromal cells (MSCs) are considered as a promising therapeutic tool for liver fibrosis, a main feature of chronic liver disease. Because small extracellular vesicles (sEVs) harboring a variety of proteins and RNAs are known to have similar functions with their derived cells, MSC-derived...

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Detalles Bibliográficos
Autores principales: Kim, Jieun, Lee, Chanbin, Shin, Yongbo, Wang, Sihyung, Han, Jinsol, Kim, Minju, Kim, Ji Min, Shin, Sung-Chan, Lee, Byung-Joo, Kim, Tae-Jin, Jung, Youngmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058446/
https://www.ncbi.nlm.nih.gov/pubmed/33348053
http://dx.doi.org/10.1016/j.ymthe.2020.12.025