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6′-O-Galloylpaeoniflorin Attenuates Osteoclasto-genesis and Relieves Ovariectomy-Induced Osteoporosis by Inhibiting Reactive Oxygen Species and MAPKs/c-Fos/NFATc1 Signaling Pathway

Emerging evidence suggests bright prospects of some natural antioxidants in the treatment of osteoporosis. 6′-O-Galloylpaeoniflorin (GPF), an antioxidant isolated from peony roots (one of very widely used Oriental medicines, with various anti-inflammatory, antitumor, and antioxidant activities), sho...

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Detalles Bibliográficos
Autores principales: Liu, Wenjie, Xie, Gang, Yuan, Guixin, Xie, Dantao, Lian, Zhen, Lin, Zihong, Ye, Jiajie, Zhou, Wenyun, Zhou, Weijun, Li, Henghui, Wang, Xinjia, Feng, Haotian, Liu, Ying, Yao, Guanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058459/
https://www.ncbi.nlm.nih.gov/pubmed/33897430
http://dx.doi.org/10.3389/fphar.2021.641277