Plasma Metabolome Signature Indicative of BRCA1 Germline Status Independent of Cancer Incidence

Individuals carrying a pathogenic germline variant in the breast cancer predisposition gene BRCA1 (gBRCA1+) are prone to developing breast cancer. Apart from its well-known role in DNA repair, BRCA1 has been shown to powerfully impact cellular metabolism. While, in general, metabolic reprogramming w...

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Detalles Bibliográficos
Autores principales: Penkert, Judith, Märtens, Andre, Seifert, Martin, Auber, Bernd, Derlin, Katja, Hille-Betz, Ursula, Hörmann, Philipp, Klopp, Norman, Prokein, Jana, Schlicker, Lisa, Wacker, Frank, Wallaschek, Hannah, Schlegelberger, Brigitte, Hiller, Karsten, Ripperger, Tim, Illig, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058469/
https://www.ncbi.nlm.nih.gov/pubmed/33898308
http://dx.doi.org/10.3389/fonc.2021.627217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058469/
https://www.ncbi.nlm.nih.gov/pubmed/33898308
http://dx.doi.org/10.3389/fonc.2021.627217

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