Telomerase therapy attenuates cardiotoxic effects of doxorubicin

Doxorubicin is one of the most potent chemotherapeutic agents. However, its clinical use is restricted due to the severe risk of cardiotoxicity, partially attributed to elevated production of reactive oxygen species (ROS). Telomerase canonically maintains telomeres during cell division but is silenc...

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Detalles Bibliográficos
Autores principales: Chatterjee, Shambhabi, Hofer, Teresa, Costa, Alessia, Lu, Dongchao, Batkai, Sandor, Gupta, Shashi Kumar, Bolesani, Emiliano, Zweigerdt, Robert, Megias, Diego, Streckfuss-Bömeke, Katrin, Brandenberger, Christina, Thum, Thomas, Bär, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058493/
https://www.ncbi.nlm.nih.gov/pubmed/33388418
http://dx.doi.org/10.1016/j.ymthe.2020.12.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058493/
https://www.ncbi.nlm.nih.gov/pubmed/33388418
http://dx.doi.org/10.1016/j.ymthe.2020.12.035

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