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Roquin is a major mediator of iron-regulated changes to transferrin receptor-1 mRNA stability

Transferrin receptor-1 (TfR1) has essential iron transport and proposed signal transduction functions. Proper TfR1 regulation is a requirement for hematopoiesis, neurological development, and the homeostasis of tissues including the intestine and muscle, while dysregulation is associated with cancer...

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Detalles Bibliográficos
Autores principales: Corral, Victor M., Schultz, Eric R., Eisenstein, Richard S., Connell, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058555/
https://www.ncbi.nlm.nih.gov/pubmed/33898949
http://dx.doi.org/10.1016/j.isci.2021.102360