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Roquin is a major mediator of iron-regulated changes to transferrin receptor-1 mRNA stability
Transferrin receptor-1 (TfR1) has essential iron transport and proposed signal transduction functions. Proper TfR1 regulation is a requirement for hematopoiesis, neurological development, and the homeostasis of tissues including the intestine and muscle, while dysregulation is associated with cancer...
Autores principales: | Corral, Victor M., Schultz, Eric R., Eisenstein, Richard S., Connell, Gregory J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058555/ https://www.ncbi.nlm.nih.gov/pubmed/33898949 http://dx.doi.org/10.1016/j.isci.2021.102360 |
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