IFN-λ4 genetic variants influence clinical malaria episodes in a cohort of Kenyan children

BACKGROUND: Interferon (IFN)- λ4, a type III IFN, production is controlled by a dinucleotide frameshift variant (rs368234815-dG/TT) within the first exon of the IFNL4 gene. Carriers of the IFNL4-dG allele but not the IFNL4-TT allele are able to produce the IFN-λ4 protein. Patients with hepatitis C v...

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Detalles Bibliográficos
Autores principales: Samayoa-Reyes, Gabriela, Jackson, Conner, Ogolla, Sidney, Sabourin, Katherine, Obajemu, Adeola, Dent, Arlene E., Prokunina-Olsson, Ludmilla, Rochford, Rosemary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058600/
https://www.ncbi.nlm.nih.gov/pubmed/33882912
http://dx.doi.org/10.1186/s12936-021-03689-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058600/
https://www.ncbi.nlm.nih.gov/pubmed/33882912
http://dx.doi.org/10.1186/s12936-021-03689-z

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