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Study on Acute Toxicity of Amiodarone New Complexes With Cyclodextrin

Amiodarone low solubility and high permeability is the limiting step for its bioavailability, therefore new formulations are needed to improve the solubility of amiodarone either to increase its oral bioavailability or to reduce its toxic effects. Complexation of amiodarone with cyclodextrin results...

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Detalles Bibliográficos
Autores principales: Ghiciuc, Cristina Mihaela, Shleghm, Maytham Razaq, Vasile, Cornelia, Tantaru, Gladiola, Creteanu, Andreea, Ochiuz, Lacramioara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058604/
https://www.ncbi.nlm.nih.gov/pubmed/33897429
http://dx.doi.org/10.3389/fphar.2021.640705