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Study on Acute Toxicity of Amiodarone New Complexes With Cyclodextrin
Amiodarone low solubility and high permeability is the limiting step for its bioavailability, therefore new formulations are needed to improve the solubility of amiodarone either to increase its oral bioavailability or to reduce its toxic effects. Complexation of amiodarone with cyclodextrin results...
Autores principales: | Ghiciuc, Cristina Mihaela, Shleghm, Maytham Razaq, Vasile, Cornelia, Tantaru, Gladiola, Creteanu, Andreea, Ochiuz, Lacramioara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058604/ https://www.ncbi.nlm.nih.gov/pubmed/33897429 http://dx.doi.org/10.3389/fphar.2021.640705 |
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