Safety and Pharmacokinetic Assessments of a Novel Ivermectin Nasal Spray Formulation in a Pig Model

Recently published data indicates that high ivermectin (IVM) concentrations suppress in vitro SARS-CoV-2 replication. Nasal IVM spray administration may contribute to attaining high drug concentrations in nasopharyngeal tissue, a primary site of virus entrance/replication. The safety and pharmacokin...

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Detalles Bibliográficos
Autores principales: Errecalde, Jorge, Lifschitz, Adrian, Vecchioli, Graciela, Ceballos, Laura, Errecalde, Francisco, Ballent, Mariana, Marín, Gustavo, Daniele, Martín, Turic, Esteban, Spitzer, Eduardo, Toneguzzo, Fernando, Gold, Silvia, Krolewiecki, Alejandro, Alvarez, Luis, Lanusse, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. on behalf of the American Pharmacists Association®. 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058614/
https://www.ncbi.nlm.nih.gov/pubmed/33493479
http://dx.doi.org/10.1016/j.xphs.2021.01.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058614/
https://www.ncbi.nlm.nih.gov/pubmed/33493479
http://dx.doi.org/10.1016/j.xphs.2021.01.017

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