Efficacy and Safety of Weekly Paclitaxel With or Without Oral Alisertib in Patients With Metastatic Breast Cancer: A Randomized Clinical Trial

IMPORTANCE: Elevated expression of AURKA adversely affects prognosis in estrogen receptor (ER)–positive and ERBB2 (formerly HER2)-negative and triple-negative breast cancer and is associated with resistance to taxanes. OBJECTIVE: To compare paclitaxel alone vs paclitaxel plus alisertib in patients w...

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Detalles Bibliográficos
Autores principales: O’Shaughnessy, Joyce, McIntyre, Kristi, Wilks, Sharon, Ma, Ling, Block, Margaret, Andorsky, David, Danso, Michael, Locke, Tracy, Scales, Amy, Wang, Yunfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058641/
https://www.ncbi.nlm.nih.gov/pubmed/33877311
http://dx.doi.org/10.1001/jamanetworkopen.2021.4103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058641/
https://www.ncbi.nlm.nih.gov/pubmed/33877311
http://dx.doi.org/10.1001/jamanetworkopen.2021.4103

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