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Saikosaponin D exhibits anti-leukemic activity by targeting FTO/m(6)A signaling
Purpose: The implementation of targeted therapies for acute myeloid leukemia (AML) has been challenging. Fat mass and obesity associated protein (FTO), an mRNA N(6)-methyladenosine (m(6)A) demethylase, functions as an oncogene that promotes leukemic oncogene-mediated cell transformation and leukemog...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058711/ https://www.ncbi.nlm.nih.gov/pubmed/33897884 http://dx.doi.org/10.7150/thno.55574 |