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Saikosaponin D exhibits anti-leukemic activity by targeting FTO/m(6)A signaling

Purpose: The implementation of targeted therapies for acute myeloid leukemia (AML) has been challenging. Fat mass and obesity associated protein (FTO), an mRNA N(6)-methyladenosine (m(6)A) demethylase, functions as an oncogene that promotes leukemic oncogene-mediated cell transformation and leukemog...

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Detalles Bibliográficos
Autores principales:	Sun, Kaiju, Du, Yangyang, Hou, Yuzhu, Zhao, Mingyue, Li, Jiajia, Du, Yazhe, Zhang, Lingxiao, Chen, Changbao, Yang, Hongmei, Yan, Fei, Su, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058711/ https://www.ncbi.nlm.nih.gov/pubmed/33897884 http://dx.doi.org/10.7150/thno.55574

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