Cargando…

MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer

Rationale: Resistance to androgen-deprivation therapy (ADT) associated with metastatic progression remains a challenging clinical task in prostate cancer (PCa) treatment. Current targeted therapies for castration-resistant prostate cancer (CRPC) are not durable. The exact molecular mechanisms mediat...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qiji, Wang, Min, Hu, Yanqing, Zhao, Ensi, Li, Jun, Ren, Liangliang, Wang, Meng, Xu, Yuandong, Liang, Qian, Zhang, Di, Lai, Yingrong, Liu, Shaoyu, Peng, Xinsheng, Zhu, Chengming, Ye, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058714/
https://www.ncbi.nlm.nih.gov/pubmed/33897882
http://dx.doi.org/10.7150/thno.56604