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Extracellular vesicles derived from M1 macrophages deliver miR-146a-5p and miR-146b-5p to suppress trophoblast migration and invasion by targeting TRAF6 in recurrent spontaneous abortion

Rationale: Emerging evidence demonstrates that insufficient migration and invasion of trophoblasts play critical roles in the pathogenesis of recurrent spontaneous abortion (RSA). Cell-to-cell communication at the maternal-fetal interface is essential to maintain the invasion and migration of tropho...

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Detalles Bibliográficos
Autores principales: Ding, Jinli, Zhang, Yan, Cai, Xiaopeng, Zhang, Yi, Yan, Sisi, Wang, Jiayu, Zhang, Sainan, Yin, Tailang, Yang, Chaogang, Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058722/
https://www.ncbi.nlm.nih.gov/pubmed/33897883
http://dx.doi.org/10.7150/thno.58731