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The PSMD14 inhibitor Thiolutin as a novel therapeutic approach for esophageal squamous cell carcinoma through facilitating SNAIL degradation

Metastasis and chemoresistance are major causes of poor prognosis in patients with esophageal squamous cell carcinoma (ESCC), manipulated by multiple factors including deubiquitinating enzyme (DUB). DUB PSMD14 is reported to be a promising therapeutic target in various cancers. Here, we explored the...

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Detalles Bibliográficos
Autores principales: Jing, Chao, Li, Xingchen, Zhou, Mengqian, Zhang, Shengchi, Lai, Qingchuan, Liu, Dandan, Ye, Beibei, Li, Linqi, Wu, Yue, Li, Hong, Yue, Kai, Chen, Peng, Yao, Xiaofeng, Wu, Yansheng, Duan, Yuansheng, Wang, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058732/
https://www.ncbi.nlm.nih.gov/pubmed/33897885
http://dx.doi.org/10.7150/thno.46109