Crosstalk between coagulation and complement activation promotes cardiac dysfunction in arrhythmogenic right ventricular cardiomyopathy

Aims: We previously found that complement components are upregulated in the myocardium of patients with arrhythmogenic right ventricular cardiomyopathy (ARVC), and inhibiting the complement receptor C5aR reduces disease severity in desmin knockout (Des(-/-)) mice, a model for ARVC. Here, we examined...

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Detalles Bibliográficos
Autores principales: Ren, Jie, Tsilafakis, Konstantinos, Chen, Liang, Lekkos, Konstantinos, Kostavasili, Ioanna, Varela, Aimilia, Cokkinos, Dennis V., Davos, Constantinos H., Sun, Xiaogang, Song, Jiangping, Mavroidis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058736/
https://www.ncbi.nlm.nih.gov/pubmed/33897891
http://dx.doi.org/10.7150/thno.58160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058736/
https://www.ncbi.nlm.nih.gov/pubmed/33897891
http://dx.doi.org/10.7150/thno.58160

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