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Inferring cancer progression from Single-Cell Sequencing while allowing mutation losses
MOTIVATION: In recent years, the well-known Infinite Sites Assumption has been a fundamental feature of computational methods devised for reconstructing tumor phylogenies and inferring cancer progressions. However, recent studies leveraging single-cell sequencing (SCS) techniques have shown evidence...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058767/ https://www.ncbi.nlm.nih.gov/pubmed/32805010 http://dx.doi.org/10.1093/bioinformatics/btaa722 |