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AMPKα2 activation by an energy-independent signal ensures chromosomal stability during mitosis

AMP-activated protein kinase (AMPK) senses energy status and impacts energy-consuming events by initiating metabolism regulatory signals in cells. Accumulating evidences suggest a role of AMPK in mitosis regulation, but the mechanism of mitotic AMPK activation and function remains elusive. Here we r...

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Detalles Bibliográficos
Autores principales: Lu, Jianlin, Huang, Yuanyuan, Zhan, Li, Wang, Ming, Xu, Leilei, Mullen, McKay, Zang, Jianye, Fang, Guowei, Dou, Zhen, Liu, Xing, Liu, Wei, Garcia-Barrio, Minerva, Yao, Xuebiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059055/
https://www.ncbi.nlm.nih.gov/pubmed/33898950
http://dx.doi.org/10.1016/j.isci.2021.102363