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Epigenetic Consequences of in Utero Exposure to Rosuvastatin: Alteration of Histone Methylation Patterns in Newborn Rat Brains

Rosuvastatin (RST) is primarily used to treat high cholesterol levels. As it has potentially harmful but not well-documented effects on embryos, RST is contraindicated during pregnancy. To demonstrate whether RST could induce molecular epigenetic events in the brains of newborn rats, pregnant mother...

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Detalles Bibliográficos
Autores principales: Dulka, Karolina, Szabo, Melinda, Lajkó, Noémi, Belecz, István, Hoyk, Zsófia, Gulya, Karoly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059142/
https://www.ncbi.nlm.nih.gov/pubmed/33810299
http://dx.doi.org/10.3390/ijms22073412