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Mechanics of a molecular mousetrap—nucleation-limited innate immune signaling

Innate immune responses, such as cell death and inflammatory signaling, are typically switch-like in nature. They also involve “prion-like” self-templating polymerization of one or more signaling proteins into massive macromolecular assemblies known as signalosomes. Despite the wealth of atomic-reso...

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Detalles Bibliográficos
Autores principales: Rodríguez Gama, Alejandro, Miller, Tayla, Halfmann, Randal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059202/
https://www.ncbi.nlm.nih.gov/pubmed/33460595
http://dx.doi.org/10.1016/j.bpj.2021.01.007