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Mechanics of a molecular mousetrap—nucleation-limited innate immune signaling
Innate immune responses, such as cell death and inflammatory signaling, are typically switch-like in nature. They also involve “prion-like” self-templating polymerization of one or more signaling proteins into massive macromolecular assemblies known as signalosomes. Despite the wealth of atomic-reso...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059202/ https://www.ncbi.nlm.nih.gov/pubmed/33460595 http://dx.doi.org/10.1016/j.bpj.2021.01.007 |