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Defective monocyte-derived macrophage phagocytosis is associated with exacerbation frequency in COPD
BACKGROUND: Lower airway bacterial colonisation (LABC) in COPD patients is associated with increased exacerbation frequency and faster lung function decline. Defective macrophage phagocytosis in COPD drives inflammation, but how defective macrophage function contributes to exacerbations is not clear...
Autores principales: | Singh, R., Belchamber, K. B. R., Fenwick, P. S., Chana, K., Donaldson, G., Wedzicha, J. A., Barnes, P. J., Donnelly, L. E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059282/ https://www.ncbi.nlm.nih.gov/pubmed/33879129 http://dx.doi.org/10.1186/s12931-021-01718-8 |
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