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Clinical Utility of Droplet Digital PCR to Monitor BCR-ABL1 Transcripts of Patients With Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia Post-chimeric Antigen Receptor19/22 T-Cell Cocktail Therapy
Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph(+) ALL) accounts for 20–30% of adult patients with ALL, characterized by translocation of t((9, 22)). Tyrosine kinase inhibitors (TKIs) have significantly improved the outcome even though there are still some problems including relaps...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059437/ https://www.ncbi.nlm.nih.gov/pubmed/33898316 http://dx.doi.org/10.3389/fonc.2021.646499 |