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Metamorphic proteins: the Janus proteins of structural biology
The structural paradigm that the sequence of a protein encodes for a unique three-dimensional native fold does not acknowledge the intrinsic plasticity encapsulated in conformational free energy landscapes. Metamorphic proteins are a recently discovered class of biomolecules that illustrate this pla...
Autores principales: | Madhurima, Kulkarni, Nandi, Bodhisatwa, Sekhar, Ashok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059507/ https://www.ncbi.nlm.nih.gov/pubmed/33878950 http://dx.doi.org/10.1098/rsob.210012 |
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