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MET-Pyk2 Axis Mediates Acquired Resistance to FGFR Inhibition in Cancer Cells

Deregulation of fibroblast growth factor receptors (FGFRs) signaling, as a result of FGFR amplification, chromosomal translocation, or mutations, is involved in both initiation and progression of a wide range of human cancers. Clinical data demonstrating the dependence of cancer cells on FGFRs signa...

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Detalles Bibliográficos
Autores principales: Kitowska, Kamila, Gorska-Arcisz, Monika, Antoun, Dima, Zarczynska, Izabela, Czaplinska, Dominika, Szczepaniak, Adrian, Skladanowski, Andrzej C., Wieczorek, Maciej, Stanczak, Aleksandra, Skupinska, Monika, Sadej, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059549/
https://www.ncbi.nlm.nih.gov/pubmed/33898310
http://dx.doi.org/10.3389/fonc.2021.633410