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MET-Pyk2 Axis Mediates Acquired Resistance to FGFR Inhibition in Cancer Cells
Deregulation of fibroblast growth factor receptors (FGFRs) signaling, as a result of FGFR amplification, chromosomal translocation, or mutations, is involved in both initiation and progression of a wide range of human cancers. Clinical data demonstrating the dependence of cancer cells on FGFRs signa...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059549/ https://www.ncbi.nlm.nih.gov/pubmed/33898310 http://dx.doi.org/10.3389/fonc.2021.633410 |