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Genome instability and loss of protein homeostasis: converging paths to neurodegeneration?

Genome instability and loss of protein homeostasis are hallmark events of age-related diseases that include neurodegeneration. Several neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's disease and amyotrophic lateral sclerosis are characterized...

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Detalles Bibliográficos
Autores principales: Ainslie, Anna, Huiting, Wouter, Barazzuol, Lara, Bergink, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8059563/
https://www.ncbi.nlm.nih.gov/pubmed/33878947
http://dx.doi.org/10.1098/rsob.200296