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Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation

Corneal neovascularization (CNV) causes higher-order aberrations, corneal edema, ocular inflammation, and corneal transplant rejection, thereby decreasing visual acuity. In this study, we investigated the effects of topical administration of the kappa opioid receptor agonist nalfurafine (TRK-820) on...

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Detalles Bibliográficos
Autores principales: Shokirova, Hurramhon, Inomata, Takenori, Saitoh, Tsuyoshi, Zhu, Jun, Fujio, Kenta, Okumura, Yuichi, Yanagawa, Ai, Fujimoto, Keiichi, Sung, Jaemyoung, Eguchi, Atsuko, Miura, Maria, Nagino, Ken, Hirosawa, Kunihiko, Kuwahara, Mizu, Akasaki, Yasutsugu, Nagase, Hiroshi, Murakami, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060258/
https://www.ncbi.nlm.nih.gov/pubmed/33883646
http://dx.doi.org/10.1038/s41598-021-88118-6