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Intranasal powder live attenuated influenza vaccine is thermostable, immunogenic, and protective against homologous challenge in ferrets

Influenza viruses cause annual seasonal epidemics and sporadic pandemics; vaccination is the most effective countermeasure. Intranasal live attenuated influenza vaccines (LAIVs) are needle-free, mimic the natural route of infection, and elicit robust immunity. However, some LAIVs require reconstitut...

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Detalles Bibliográficos
Autores principales: Luczo, Jasmina M., Bousse, Tatiana, Johnson, Scott K., Jones, Cheryl A., Pearce, Nicholas, Neiswanger, Carlie A., Wang, Min-Xuan, Miller, Erin A., Petrovsky, Nikolai, Wentworth, David E., Bronshtein, Victor, Papania, Mark, Tompkins, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060263/
https://www.ncbi.nlm.nih.gov/pubmed/33883559
http://dx.doi.org/10.1038/s41541-021-00320-9