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A comprehensive characterization of the cell-free transcriptome reveals tissue- and subtype-specific biomarkers for cancer detection

Cell-free RNA (cfRNA) is a promising analyte for cancer detection. However, a comprehensive assessment of cfRNA in individuals with and without cancer has not been conducted. We perform the first transcriptome-wide characterization of cfRNA in cancer (stage III breast [n = 46], lung [n = 30]) and no...

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Detalles Bibliográficos
Autores principales: Larson, Matthew H., Pan, Wenying, Kim, Hyunsung John, Mauntz, Ruth E., Stuart, Sarah M., Pimentel, Monica, Zhou, Yiqi, Knudsgaard, Per, Demas, Vasiliki, Aravanis, Alexander M., Jamshidi, Arash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060291/
https://www.ncbi.nlm.nih.gov/pubmed/33883548
http://dx.doi.org/10.1038/s41467-021-22444-1