Directed evolution for high functional production and stability of a challenging G protein-coupled receptor

Membrane proteins such as G protein-coupled receptors (GPCRs) carry out many fundamental biological functions, are involved in a large number of physiological responses, and are thus important drug targets. To allow detailed biophysical and structural studies, most of these important receptors have...

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Detalles Bibliográficos
Autores principales: Waltenspühl, Yann, Jeliazkov, Jeliazko R., Kummer, Lutz, Plückthun, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060309/
https://www.ncbi.nlm.nih.gov/pubmed/33883583
http://dx.doi.org/10.1038/s41598-021-87793-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060309/
https://www.ncbi.nlm.nih.gov/pubmed/33883583
http://dx.doi.org/10.1038/s41598-021-87793-9

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