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Development and evaluation of physiologically based pharmacokinetic drug-disease models for predicting captopril pharmacokinetics in chronic diseases

The advancement in the processing speeds of computing machines has facilitated the development of complex physiologically based pharmacokinetic (PBPK) models. These PBPK models can incorporate disease-specific data and could be used to predict pharmacokinetics (PK) of administered drugs in different...

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Detalles Bibliográficos
Autores principales: Rasool, Muhammad F., Ali, Shazia, Khalid, Sundus, Khalid, Ramsha, Majeed, Abdul, Imran, Imran, Saeed, Hamid, Usman, Muhammad, Ali, Mohsin, Alali, Amer S., AlAsmari, Abdullah F., Ali, Nemat, Asiri, Ali Mohammed, Alasmari, Fawaz, Alqahtani, Faleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060346/
https://www.ncbi.nlm.nih.gov/pubmed/33883647
http://dx.doi.org/10.1038/s41598-021-88154-2