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GLUT1 overexpression enhances glucose metabolism and promotes neonatal heart regeneration

The mammalian heart switches its main metabolic substrate from glucose to fatty acids shortly after birth. This metabolic switch coincides with the loss of regenerative capacity in the heart. However, it is unknown whether glucose metabolism regulates heart regeneration. Here, we report that glucose...

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Detalles Bibliográficos
Autores principales: Fajardo, Viviana M., Feng, Iris, Chen, Bao Ying, Perez-Ramirez, Cesar A., Shi, Baochen, Clark, Peter, Tian, Rong, Lien, Ching-Ling, Pellegrini, Matteo, Christofk, Heather, Nakano, Haruko, Nakano, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060418/
https://www.ncbi.nlm.nih.gov/pubmed/33883682
http://dx.doi.org/10.1038/s41598-021-88159-x