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GLUT1 overexpression enhances glucose metabolism and promotes neonatal heart regeneration
The mammalian heart switches its main metabolic substrate from glucose to fatty acids shortly after birth. This metabolic switch coincides with the loss of regenerative capacity in the heart. However, it is unknown whether glucose metabolism regulates heart regeneration. Here, we report that glucose...
Autores principales: | Fajardo, Viviana M., Feng, Iris, Chen, Bao Ying, Perez-Ramirez, Cesar A., Shi, Baochen, Clark, Peter, Tian, Rong, Lien, Ching-Ling, Pellegrini, Matteo, Christofk, Heather, Nakano, Haruko, Nakano, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060418/ https://www.ncbi.nlm.nih.gov/pubmed/33883682 http://dx.doi.org/10.1038/s41598-021-88159-x |
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