Fiber Derived Microbial Metabolites Prevent Acute Kidney Injury Through G-Protein Coupled Receptors and HDAC Inhibition

Short-chain fatty acids (SCFA) derived from gut microbial fermentation of fiber have been shown to exert anti-inflammatory and immune-modulatory properties in acute kidney injury (AKI). However the direct mechanistic link between SCFAs, diet and the gut microbiome is yet to be established. Using the...

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Detalles Bibliográficos
Autores principales: Liu, Yunzi, Li, Yan J., Loh, Yik W., Singer, Julian, Zhu, Weiping, Macia, Laurence, Mackay, Charles R., Wang, Weiming, Chadban, Steven J., Wu, Huiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060457/
https://www.ncbi.nlm.nih.gov/pubmed/33898439
http://dx.doi.org/10.3389/fcell.2021.648639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060457/
https://www.ncbi.nlm.nih.gov/pubmed/33898439
http://dx.doi.org/10.3389/fcell.2021.648639

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